An Efficient Multi path Dynamic Routing Protocol for Computing and Constrained Mobile Ad-hoc Network Environment

Wireless mobile ad-hoc networks are classified as ad-hoc networks with logical connections. These types of networks do not have fixed topology (or physical connections) due to the mobility property of nodes, interference, propagation and loss of path. Because of all these problems the path established between sources to destination is not reliable and efficient path. Hence a dynamic source routing protocol is required for these networks to working properly. Data transfer using this protocol based on shorted path, all packets need to be transferred using same path. The researcher on MANET proposed many Routing algorithms to this task. The main idea of this paper is to study, understand, and analyze the problems with existing routing methods. In the proposed multi path dynamic routing, first identify multi paths exist between source to destination and select best shortest path and then data is segmented into packets, each packet is transferred to receiver using selected best shortest path. At receiver end received data need to be rearranged. Finally the performance proposed system is compared with existing methods and proposed method shows better performance when compared with existing methods

REARRANGE BASED ON IDENTITY AND APPLICATION IN EMAIL IN THE CLOUD

Within a CIBPRE system, a trusted key generation center initializes the CIBPRE machine parameters and generates private keys for users. To securely share files to multiple recipients, a sender can secure the files by using the recipients' identities and file discussion conditions. If the sender later wishes to talk about some files related to a similar condition together with other receivers, the sender can delegate a tagged re-encrypted encryption key using the condition for the proxy, as well as the parameters to create the encryption secret of re-archiving. It is beyond the original recipients of these files. Conditional PREs, based on identity and transmission PREs, are suggested for flexible applications. CIBPRE allows a sender to secure a note to multiple receivers by indicating the identities of those receivers, and can also delegate a re-encryption encryption response to a proxy to convert the first encrypted text into a substitute for a different group of recipients. Recipients by CPRE, IPRE and BPRE, this document proposes a flexible primitive known as conditional emission based on PRE identity and formalizes its semantic security. In addition, the re-encryption encryption key can be connected with a condition so that only the corresponding encryption texts can be encrypted again, allowing the initial sender to enforce access control of their remote encryption texts in a very detailed. Finally, we show a credit card application on our CIBPRE to protect the cloud email system that is beneficial to existing secure email systems according to very good privacy protocol or file-based encryption identity

Phytochemical investigations and antibacterial activity of Salacia oblonga Wall ethanolic extract

Abstract Salacia oblonga Wall, a medicinally important plant, belonging to the family Celastraceae, is a large woody climber distributed in southern India and Sri Lanka. In the present investigation, ethanol extracts of S. oblonga were prepared from aerial and root parts of the plant in the presence and absence of HCl and antibacterial activity was tested. Both aerial and root extracts exhibited pronounced activity against human pathogens. The MIC and MBC values ranged from 0.078-1.25 mg/ml and 0.156 -2.50 mg/ml, respectively. GC-MS profile of aerial and root extracts displayed the presence of 11 and 6 compounds. The present investigation demonstrated that ethanolic extracts of S. oblonga have potential antibacterial activity against human pathogens and could serve as a source for the development of new age antimicrobials

A Clinical Study on Vrana Shodhana Action of Gomutra Arka in Dushtavrana w.s.r. to Diabetic Foot Ulcer

Context: The diabetic foot ulcer, being chronic in nature involves various tissues, it can be considered as Dushtavrana in Ayurveda. Proper Care for diabetic foot with medication and procedures that has hastened the healing process with less complication is the need of the hour. Aim: To evaluate the Vrana Shodhana action of Gomutra Arka in Dushtavrana w.s.r. to diabetic foot ulcers. Settings and Design: It is a clinical study with pre-test and post-test design. Total number of patient’s taken for the study was 40 excluding dropouts. The patients selected for the study were divided in to 2 groups, Group-A and Group-B, consisting of 20 patients each. Materials and Methods: The wound is examined, exudates, debris, slough were removed, the surrounding area was cleaned and pad soaked in Gomutra Arka was placed and wound dressing was done once in a day. Duration of study was 45 days or till the formation of granulation tissue whichever is earlier, assessment was done every 7 days. For healing Jatyadi Taila was applied after the Shodhana Kriya with Gomutra Arka. Conclusion: Gomutra Arka was having good results in reducing burning sensation, itching, smell, size, depth, discharge, edge, floor and presence of granulation tissues compared to Betadine. Both drugs have equal effect in reducing pain. Both drugs have Shodhana, Lekhana properties, hastens the wound healing process which helps in reduction of wound size. It can be concluded that Gomutra Arka application is effective in all types of Diabetic foot ulcer by their faster, effective Shodhana, Lekhana, Vedana Shamaka, Kandu Shamaka, Daha Shamaka properties compared to Betadine

A NOVEL ENTER WORD SEARCH WITH NOMINATED TESTER AND TIMING FACILITATE EXCHANGE RE CIPHER TEXT ROLE FOR ONLINE PHYSICAL CLOUDS

The Search File Encryption (SE) plan is indeed a technology that includes security and favorable functionality that can play a very important role in the e-health registration system. The Digital Health Information Product is a unique application that offers great comfort in healthcare. In this document, we present a unique encryption primitive, called a common search engine for the searcher, and a timing-enabled proxy transfer encryption, which is a time-dependent SE plan. We designed a unique search file encryption plan that supports secure search for affiliate keywords and approved broadcast functionality. Unlike in existing systems, work can synchronize the re-encryption of the proxy file allowed by effective cancellation of the delegation. The security and privacy of sensitive private data are major user concerns that may hinder the development and widespread deployment of systems. We create a method model together with a security model so that the proposed Re-dtPECK plan shows that it is a skilled plan that has proven to be safe in a standard model. Comparison and large-scale simulations show that it represents low computation and storage. It could allow patients to transfer the legal rights of others to a partial use to perform search operations on their records within a short period of time. The time period during which the Trustee can view and decrypt the Trusted Encrypted Document can be managed

Cardiovascular magnetic resonance of myocardial edema using a short inversion time inversion recovery (STIR) black-blood technique: Diagnostic accuracy of visual and semi-quantitative assessment

<p>Abstract</p> <p>Background</p> <p>The short inversion time inversion recovery (STIR) black-blood technique has been used to visualize myocardial edema, and thus to differentiate acute from chronic myocardial lesions. However, some cardiovascular magnetic resonance (CMR) groups have reported variable image quality, and hence the diagnostic value of STIR in routine clinical practice has been put into question. The aim of our study was to analyze image quality and diagnostic performance of STIR using a set of pulse sequence parameters dedicated to edema detection, and to discuss possible factors that influence image quality. We hypothesized that STIR imaging is an accurate and robust way of detecting myocardial edema in non-selected patients with acute myocardial infarction.</p> <p>Methods</p> <p>Forty-six consecutive patients with acute myocardial infarction underwent CMR (day 4.5, +/- 1.6) including STIR for the assessment of myocardial edema and late gadolinium enhancement (LGE) for quantification of myocardial necrosis. Thirty of these patients underwent a follow-up CMR at approximately six months (195 +/- 39 days). Both STIR and LGE images were evaluated separately on a segmental basis for image quality as well as for presence and extent of myocardial hyper-intensity, with both visual and semi-quantitative (threshold-based) analysis. LGE was used as a reference standard for localization and extent of myocardial necrosis (acute) or scar (chronic).</p> <p>Results</p> <p>Image quality of STIR images was rated as diagnostic in 99.5% of cases. At the acute stage, the sensitivity and specificity of STIR to detect infarcted segments on visual assessment was 95% and 78% respectively, and on semi-quantitative assessment was 99% and 83%, respectively. STIR differentiated acutely from chronically infarcted segments with a sensitivity of 95% by both methods and with a specificity of 99% by visual assessment and 97% by semi-quantitative assessment. The extent of hyper-intense areas on acute STIR images was 85% larger than those on LGE images, with a larger myocardial salvage index in reperfused than in non-reperfused infarcts (p = 0.035).</p> <p>Conclusions</p> <p>STIR with appropriate pulse sequence settings is accurate in detecting acute myocardial infarction (MI) and distinguishing acute from chronic MI with both visual and semi-quantitative analysis. Due to its unique technical characteristics, STIR should be regarded as an edema-weighted rather than a purely T2-weighted technique.</p

Hollow mesoporous silica nanoparticles for intracellular delivery of fluorescent dye

In this study, hollow mesoporous silica nanoparticles (HMSNs) were synthesized using the sol-gel/emulsion approach and its potential application in drug delivery was assessed. The HMSNs were characterized, by transmission electron microscopy (TEM), Scanning Electron Microscopy (SEM), nitrogen adsorption/desorption and Brunauer-Emmett-Teller (BET), to have a mesoporous layer on its surface, with an average pore diameter of about 2 nm and a surface area of 880 m2/g. Fluorescein isothiocyanate (FITC) loaded into these HMSNs was used as a model platform to assess its efficacy as a drug delivery tool. Its release kinetic study revealed a sequential release of FITC from the HMSNs for over a period of one week when soaked in inorganic solution, while a burst release kinetic of the dye was observed just within a few hours of soaking in organic solution. These FITC-loaded HMSNs was also found capable to be internalized by live human cervical cancer cells (HeLa), wherein it was quickly released into the cytoplasm within a short period of time after intracellular uptake. We envision that these HMSNs, with large pores and high efficacy to adsorb chemicals such as the fluorescent dye FITC, could serve as a delivery vehicle for controlled release of chemicals administered into live cells, opening potential to a diverse range of applications including drug storage and release as well as metabolic manipulation of cells

Identification of myocardial diffuse fibrosis by 11 heartbeat MOLLI T1 mapping: averaging to improve precision and correlation with collagen volume fraction

Objectives: Our objectives involved identifying whether repeated averaging in basal and mid left ventricular myocardial levels improves precision and correlation with collagen volume fraction for 11 heartbeat MOLLI T1 mapping versus assessment at a single ventricular level. Materials and methods: For assessment of T1 mapping precision, a cohort of 15 healthy volunteers underwent two CMR scans on separate days using an 11 heartbeat MOLLI with a 5(3)3 beat scheme to measure native T1 and a 4(1)3(1)2 beat post-contrast scheme to measure post-contrast T1, allowing calculation of partition coefficient and ECV. To assess correlation of T1 mapping with collagen volume fraction, a separate cohort of ten aortic stenosis patients scheduled to undergo surgery underwent one CMR scan with this 11 heartbeat MOLLI scheme, followed by intraoperative tru-cut myocardial biopsy. Six models of myocardial diffuse fibrosis assessment were established with incremental inclusion of imaging by averaging of the basal and mid-myocardial left ventricular levels, and each model was assessed for precision and correlation with collagen volume fraction. Results: A model using 11 heart beat MOLLI imaging of two basal and two mid ventricular level averaged T1 maps provided improved precision (Intraclass correlation 0.93 vs 0.84) and correlation with histology (R2 = 0.83 vs 0.36) for diffuse fibrosis compared to a single mid-ventricular level alone. ECV was more precise and correlated better than native T1 mapping. Conclusion: T1 mapping sequences with repeated averaging could be considered for applications of 11 heartbeat MOLLI, especially when small changes in native T1/ECV might affect clinical management